Journal of Medical and Surgical
Research (JMSR)


...

Pages: 1224-1228DOI: 10.46327/msrjg.1.000000000000247

Date of Publication: 30-Nov--0001

Glycemic Control and Overweight/Obesity among Type 2 Diabetes Moroccan Patients According to a Secondary Care Referral Center in Oujda- Morocco.

Author: Naima Abda, Mohammed Amine Bouazzaoui, Hasna Dahmani, Yassamine Bentata

Category: JMSR Diabetes & Endocriniology

[Download PDF]

Abstract:

Background: Maintaining optimal glycemic control is a primary goal in the management of type 2 diabetes, especially among overweight and obese patients. The objective of the study was to explore the relationship between overweight/obesity and glycemic control (HbA1c) among patients diagnosed with diabetes mellitus and admitted to the reference center for chronic diseases in Oujda. Methods: This is a retrospective cohort study including all type 2 diabetic patients who had at least 2 consultations between 2005 and December 2020. Results: 5123 patients were included in the study, 71.6% were women with an average age of 56.6 ---PlusMinusSymbol--- 11.8 years and 54.8% had diabetes for more than 2.5 years. Arterial hypertension was present in 38.3% at admission, 43.2% were overweight and 30.1% were obese. Almost 16.3% of patients had at least one complication on admission, 3.5% had heart disease, 5% had nephropathy, 3.9% retinopathy, 1.3% neuropathy and 0.6 % had a diabetic foot. During the 2nd visit, almost a quarter (23.7%) of overweight/obese patients had good glycemic control versus 20.5% in patients with an underweight or normal weight patients (p=0.035) with a more marked decrease of HbA1C between the 1st and the 2nd visit in overweight/obese patients (8.9---PlusMinusSymbol---0.1% versus 8.8---PlusMinusSymbol--- 0.1%, p=0.054) compared to underweight or normal weight patients (9.4---PlusMinusSymbol--- 0.1% versus 9.3---PlusMinusSymbol--- 0.1%, p=0.318). The overweight/obese patients were significantly younger than the others (55.4---PlusMinusSymbol---11.3 years versus 56.7 ---PlusMinusSymbol---9.4 years, p=0.002), with more comorbidities, more history of hypertension (39.7% versus 28%, p

Keywords: Diabetes, glycemic control, overweight, obesity, Morocco

References:

1. Word Health Organization (WHO). Diabetes factsheet [Internet]. [cité 18 mai 2023]. Disponible sur: https://www.who.int/news-room/fact-sheets/detail/diabetes

2. Pengpid S, Peltzer K. Prevalence and correlates of undiagnosed, diagnosed, and total type 2 diabetes among adults in Morocco, 2017. Sci Rep. 27 sept 2022;12(1):16092.

3. Boye KS, Lage MJ, Thieu V, Shinde S, Dhamija S, Bae JP. Obesity and glycemic control among people with type 2 diabetes in the United States: A retrospective cohort study using insurance claims data. J Diabetes Complications. sept 2021;35(9):107975.

4. Chetoui A, Kaoutar K, Boutahar K, El Kardoudi A, Elmoussaoui S, Chigr F, et al. Prevalence of overweight/obesity and its associated factors among a sample of Moroccan type 2 diabetes patients. Afr Health Sci. mars 2021;21(1):23?31.

5. ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, et al. 6. Glycemic Targets: Standards of Care in Diabetes—2023. Diabetes Care. 12 déc 2022;46(Supplement_1):S97?110.

6. Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 15 août 2006;145(4):247?54.

7. Anothaisintawee T, Rattanasiri S, Ingsathit A, Attia J, Thakkinstian A. Prevalence of chronic kidney disease: a systematic review and meta-analysis. Clin Nephrol. 1 mars 2009;71(03):244?54.

8. Ministry of Health Morocco. National survey of noncommunicable diseases risk factors 2017-2018 [Internet]. Disponible sur: https://www.sante.gov.ma/Documents/2019/05/Rapport%20de%20l%20enqu%C3%AAte%20Stepwise.pdf

9. Maggio CA, Pi-Sunyer FX. Obesity and type 2 diabetes. Endocrinol Metab Clin North Am. déc 2003;32(4):805?22, viii.

10. Ramalingam L, Menikdiwela K, LeMieux M, Dufour JM, Kaur G, Kalupahana N, et al. The renin angiotensin system, oxidative stress and mitochondrial function in obesity and insulin resistance. Biochim Biophys Acta Mol Basis Dis. mai 2017;1863(5):1106?14.

11. Chan WB, Tong PCY, Chow CC, So WY, Ng MCY, Ma RCW, et al. The associations of body mass index, C-peptide and metabolic status in Chinese Type 2 diabetic patients. Diabet Med J Br Diabet Assoc. avr 2004;21(4):349?53.

12. Lotfi Z, Aboussaleh Y, Sbaibi R, Achouri I, Benguedour R. Le surpoids, l’obésité et le contrôle glycémique chez les diabétiques du centre de référence provincial de diabète (CRD), Kénitra, Maroc. Pan Afr Med J. 11 juill 2017;27:189.

13. Kennedy-Martin T, Robinson S, Boye K. PDB81 Literature Review on the Association between BMI and Glycemic Control in Patients with Type 2 Diabetes across Eight Countries. Value Health. 1 déc 2020;23:S519.