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<PublisherName>journal-jmsr</PublisherName>
<JournalTitle>Journal of Medical and Surgical Research</JournalTitle>
<PISSN>I</PISSN>
<EISSN>S</EISSN>
<Volume-Issue>Vol. VII, n 2</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>December, 2020</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
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<ArticleType>JMSR Pathology</ArticleType>
<ArticleTitle>Microscopical Findings in COVID-19: which Diversity?</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>870</FirstPage>
<LastPage>877</LastPage>
<AuthorList>
<Author>
<FirstName>Karima Idrissi</FirstName>
<LastName>Serhrouchni</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Jinane</FirstName>
<LastName>Kharmoum</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Adil</FirstName>
<LastName>Najdi</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Mariame</FirstName>
<LastName>Chraibi</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
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<DOI>10.46327/msrjg.1.000000000000184</DOI>
<Abstract>Purpose: The main goal of this paper is to present a review study of the different publications reporting histopathological findings regarding SARS-COV-2 from the beginning of the epidemic till today in order to use the overall finding to clarify the pathogenesis. Methods: A literature review was carried out. Relevant papers were identified and Data related to general settings and pathological features of patients COVID-19 were extracted, classed and compared. Results: Seven publications were examined. Overall 80 patients COVID-19 underwent histopathological examination. There was a general predominance of males. Range of age mean (50 - 78.5). The features of the exudative and proliferative phases of Diffuse Alveolar Disease (DAD) were noted in the diverse series: capillary congestion, necrosis of pneumocytes, hyaline membrane, interstitial edema, pneumocyte hyperplasia and reactive atypia. Although, thromboembolic events were as well reported in patients with COVID-19. Conclusion and perspectives: We try to understand the pathogenesis of SARS-COV-2 and the molecular events triggered by its binding to target organs receptors, mainly the lung. It will be probably the subject of new therapeutic methods.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>CoVID-19 pathogenicity, Diffuse alveolar damage, Microthrombi, SARS-CoV-2</Keywords>
<URLs>
<Abstract>https://www.journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=8369&title=Microscopical Findings in COVID-19: which Diversity?</Abstract>
</URLs>
<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
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