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    <Journal>
      <PublisherName>journal-jmsr</PublisherName>
      <JournalTitle>Journal of Medical and Surgical Research</JournalTitle>
      <PISSN>I</PISSN>
      <EISSN>S</EISSN>
      <Volume-Issue>Vol. I, n 1 </Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>June, 2014</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>-0001</Year>
        <Month>11</Month>
        <Day>30</Day>
      </PubDate>
      <ArticleType>JMSR Oncology</ArticleType>
      <ArticleTitle>Radiation Induced Triple Localization of Squamous Cell Carcinoma of The Esophagus in a Woman Previously Treated for Breast Cancer</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>19</FirstPage>
      <LastPage>21</LastPage>
      <AuthorList>
        <Author>
          <FirstName>M. Sayed</FirstName>
          <LastName>Naya</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>A.</FirstName>
          <LastName>Benkabbou</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>H.</FirstName>
          <LastName>Hachim</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>B.</FirstName>
          <LastName>Serji</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>H.O.</FirstName>
          <LastName>Elmalki</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>R.</FirstName>
          <LastName>Mohsine</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>L.</FirstName>
          <LastName>Ifrine</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>A.</FirstName>
          <LastName>Belkouchi</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>A.</FirstName>
          <LastName>Souadka</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>Background: Radiation-induced neoplasms though very rare, had been described in long-term breast cancer survivors. Multiple primary esophageal carcinomas are extremely rare. We report a case of multiple radiation induced squamous cell carcinoma of the esophagus in a woman previously treated for left breast invasive ductal carcinoma.&#13;
&#13;
Case presentation: A 53 year old Moroccan woman, a non-smoker, with no familial history of cancer, had a dysphasia that revealed a multiple primary esophageal squamous cell carcinoma with no distant metastases. She had previous history of breast invasive ductal carcinoma classified pT3N1M0 according to TNM classification adopted by the AJCC, grade 2 of SBR (Scaff Bloom and Richardson), with positive hormone receptors. She underwent radical mastectomy, post operatively had 6 courses of adjuvant CMF regimen followed by 50 grays of external beam radiation to the breast area, supra clavicular and the inner right mammary nodes and 5 years hormonal therapy. Esophageal carcinoma occurred 20 years after the radiation, and was treated by total oesophagectomy and three field__ampersandsign#39;s lymphadenectomy. The postoperative course was dominated by an early re-intervention for mediastinal infection following an oesogastric leakage. We performed colic transplant reconstruction four months later, which was complicated by anastomotic stenosis requiring endoscopic dilatation.&#13;
&#13;
Conclusion: We reported an extremely rare case of triple location of radiation-induced esophageal carcinoma that occurred 20 years after thoracic adjuvant irradiation for breast cancer. This situation should be suspected as differential diagnosis in every patient presenting with a history of thoracic irradiation for primary malignancy no matter how long.</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>Multiple primary neoplasm, Esophageal cancer, Radiation induced neoplasm</Keywords>
      <URLs>
        <Abstract>https://www.journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=4506&amp;title=Radiation Induced Triple Localization of Squamous Cell Carcinoma of The Esophagus in a Woman Previously Treated for Breast Cancer</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
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      </References>
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