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<Journal>
<PublisherName>journal-jmsr</PublisherName>
<JournalTitle>Journal of Medical and Surgical Research</JournalTitle>
<PISSN>I</PISSN>
<EISSN>S</EISSN>
<Volume-Issue>Vol. I, n 1 </Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>June, 2014</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
</PubDate>
<ArticleType>JMSR Oncology</ArticleType>
<ArticleTitle>Radiation Induced Triple Localization of Squamous Cell Carcinoma of The Esophagus in a Woman Previously Treated for Breast Cancer</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>19</FirstPage>
<LastPage>21</LastPage>
<AuthorList>
<Author>
<FirstName>M. Sayed</FirstName>
<LastName>Naya</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>A.</FirstName>
<LastName>Benkabbou</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>H.</FirstName>
<LastName>Hachim</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>B.</FirstName>
<LastName>Serji</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>H.O.</FirstName>
<LastName>Elmalki</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>R.</FirstName>
<LastName>Mohsine</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>L.</FirstName>
<LastName>Ifrine</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>A.</FirstName>
<LastName>Belkouchi</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>A.</FirstName>
<LastName>Souadka</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
</Author>
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<DOI/>
<Abstract>Background: Radiation-induced neoplasms though very rare, had been described in long-term breast cancer survivors. Multiple primary esophageal carcinomas are extremely rare. We report a case of multiple radiation induced squamous cell carcinoma of the esophagus in a woman previously treated for left breast invasive ductal carcinoma.
Case presentation: A 53 year old Moroccan woman, a non-smoker, with no familial history of cancer, had a dysphasia that revealed a multiple primary esophageal squamous cell carcinoma with no distant metastases. She had previous history of breast invasive ductal carcinoma classified pT3N1M0 according to TNM classification adopted by the AJCC, grade 2 of SBR (Scaff Bloom and Richardson), with positive hormone receptors. She underwent radical mastectomy, post operatively had 6 courses of adjuvant CMF regimen followed by 50 grays of external beam radiation to the breast area, supra clavicular and the inner right mammary nodes and 5 years hormonal therapy. Esophageal carcinoma occurred 20 years after the radiation, and was treated by total oesophagectomy and three field__ampersandsign#39;s lymphadenectomy. The postoperative course was dominated by an early re-intervention for mediastinal infection following an oesogastric leakage. We performed colic transplant reconstruction four months later, which was complicated by anastomotic stenosis requiring endoscopic dilatation.
Conclusion: We reported an extremely rare case of triple location of radiation-induced esophageal carcinoma that occurred 20 years after thoracic adjuvant irradiation for breast cancer. This situation should be suspected as differential diagnosis in every patient presenting with a history of thoracic irradiation for primary malignancy no matter how long.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>Multiple primary neoplasm, Esophageal cancer, Radiation induced neoplasm</Keywords>
<URLs>
<Abstract>https://www.journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=4506&title=Radiation Induced Triple Localization of Squamous Cell Carcinoma of The Esophagus in a Woman Previously Treated for Breast Cancer</Abstract>
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<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
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</References>
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