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    <Journal>
      <PublisherName>journal-jmsr</PublisherName>
      <JournalTitle>Journal of Medical and Surgical Research</JournalTitle>
      <PISSN>I</PISSN>
      <EISSN>S</EISSN>
      <Volume-Issue>Vol. XII, n 2</Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>December 2025</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>-0001</Year>
        <Month>11</Month>
        <Day>30</Day>
      </PubDate>
      <ArticleType>JMSR Gastroenterology</ArticleType>
      <ArticleTitle>Prevalence and Determinants of Malnutrition Risk in Crohn__ampersandsignrsquo;s Disease: A Focus on Anthropometric and Clinical Correlates.</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>1465</FirstPage>
      <LastPage>1475</LastPage>
      <AuthorList>
        <Author>
          <FirstName>Aicha Hanae Ait El</FirstName>
          <LastName>Kounnini</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Zhor</FirstName>
          <LastName>Zeghari</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Jihane</FirstName>
          <LastName>Belayachi</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Redouane</FirstName>
          <LastName>Abouqal</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Fatima Zohra</FirstName>
          <LastName>Ajana</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>Background: Malnutrition is common in Crohn__ampersandsignrsquo;s disease, negatively impacting prognosis and contributing to various disease-related complications. The aim of our study was to assess the risk of malnutrition in these patients and to investigate its potential association with anthropometric parameters, clinical factors, and dietary restrictions.&#13;
&#13;
Materials and Methods: A cross-sectional study was conducted among patients with Crohn__ampersandsignrsquo;s disease at department __ampersandsignldquo;C__ampersandsignrdquo; Gastroenterology Department of Ibn Sina Hospital from November 2024 to April 2025. All participants underwent a consultation that included a clinical interview, anthropometric measurements using bioelectrical impedance analysis, and scoring assessments. The Saskatchewan IBD-NR score was used to evaluate malnutrition risk. Collected data were compiled in an Excel database, and a statistical analysis was performed.&#13;
&#13;
Results: A total of 159 patients with Crohn__ampersandsignrsquo;s disease were included, with a mean age of 42.2 __ampersandsignplusmn; 13.4 years and a male-to-female ratio of 0.59. Among them, 47.7% (74) were in an active disease phase, and 23.2% (44) were underweight. Dietary restrictions were reported by 104 patients (65.4%), while 38.7% (60) were found to have a high risk of malnutrition. A significant association was observed between a high risk of malnutrition and disease activity (p &lt; 0.001), dietary restriction (p &lt; 0.001), as well as FFMI (p = 0.048), FMI (p &lt; 0.001), and BMI (p &lt; 0.001).&#13;
&#13;
Conclusion: These findings highlight the significant relationship between disease activity, body composition, dietary practices, and the risk of malnutrition, emphasizing the need for comprehensive medical and nutritional management of patients with Crohn__ampersandsignrsquo;s disease.</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>Crohn's disease, inflammatory bowel diseases, malnutrition, nutritional assessment, risk of malnutrition, Saskatchewan IBD nutritional risk.</Keywords>
      <URLs>
        <Abstract>https://www.journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=16145&amp;title=Prevalence and Determinants of Malnutrition Risk in Crohn__ampersandsignrsquo;s Disease: A Focus on Anthropometric and Clinical Correlates.</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
        <References>Valentini L, Schaper L, Buning C, Hengstermann S, Koernicke T, Tillinger W, Guglielmi FW, Norman K, Buhner S, Ockenga J, Pirlich M, Lochs H. Malnutrition and impaired muscle strength in patients with Crohnand;#39;s disease and ulcerative colitis in remission. Nutrition. 2008 Jul-Aug;24(7-8):694-702. doi: 10.1016/j.nut.2008.03.018. Epub 2008 May 21. PMID: 18499398.&#13;
	Casanova MJ, Chaparro M, Molina B, Merino O, Batanero R, Dueand;ntilde;as-Sadornil C, Robledo P, Garcia-Albert AM, Gand;oacute;mez-Sand;aacute;nchez MB, Calvet X, Trallero MDR, Montoro M, Vand;aacute;zquez I, Charro M, Barragand;aacute;n A, Martand;iacute;nez-Cerezo F, Megias-Rangil I, Huguet JM, Marti-Bonmati E, Calvo M et all. Prevalence of Malnutrition and Nutritional Characteristics of Patients With Inflammatory Bowel Disease. J Crohns Colitis. 2017 Dec 4;11(12):1430-1439. doi: 10.1093/ecco-jcc/jjx102. PMID: 28981652.&#13;
	Cederholm T, Bosaeus I, Barazzoni R, Bauer J, Van Gossum A, Klek S, Muscaritoli M, Nyulasi I, Ockenga J, Schneider SM, de van der Schueren MA, Singer P. Diagnostic criteria for malnutrition - An ESPEN Consensus Statement. Clin Nutr. 2015 Jun;34(3):335-40. doi: 10.1016/j.clnu.2015.03.001. Epub 2015 Mar 9. PMID: 25799486.&#13;
	Balestrieri P, Ribolsi M, Guarino MPL, Emerenziani S, Altomare A, Cicala M. Nutritional Aspects in Inflammatory Bowel Diseases. Nutrients. 2020 Jan 31;12(2):372. doi: 10.3390/nu12020372. PMID: 32023881; PMCID: PMC7071234.&#13;
	Bin CM, Flores C, Alvares-da-Silva MR, Francesconi CF. Comparison between handgrip strength, subjective global assessment, anthropometry, and biochemical markers in assessing nutritional status of patients with Crohnand;#39;s disease in clinical remission. Dig Dis Sci. 2010 Jan;55(1):137-44. doi: 10.1007/s10620-008-0692-1. Epub 2009 Feb 20. PMID: 19229617.&#13;
	Valentini L, Schulzke JD. Mundane, yet challenging: the assessment of malnutrition in inflammatory bowel disease. Eur J Intern Med. 2011 Feb;22(1):13-5. doi: 10.1016/j.ejim.2010.07.021. PMID: 21238886.&#13;
	Jaband;#322;oand;#324;ska B, Mrowiec S. Nutritional Status and Its Detection in Patients with Inflammatory Bowel Diseases. Nutrients. 2023 Apr 20;15(8):1991. doi: 10.3390/nu15081991. PMID: 37111210; PMCID: PMC10143611.&#13;
	Kyle UG, Piccoli A, Pichard C. Body composition measurements: interpretation finally made easy for clinical use. Curr Opin Clin Nutr Metab Care. 2003 Jul;6(4):387-93. doi: 10.1097/01.mco.0000078988.18774.3d. PMID: 12806211.&#13;
	Ait El Kounnini AH, Zeghari Z, Belayachi J, Abouqal R, Ajana FZ. Quality of Life Among Crohnand;rsquo;s Disease Patients in Morocco: A Cross-Sectional Study. J Med Surg Res. 2025 Aug;12(1):1448-1458. doi:10.46327/msrjg.1.000000000000271..&#13;
	Torres J, Mehandru S, Colombel JF, Peyrin-Biroulet L. Crohnand;#39;s disease. Lancet. 2017 Apr 29;389(10080):1741-1755. doi: 10.1016/S0140-6736(16)31711-1. Epub 2016 Dec 1. PMID: 27914655.&#13;
	Fraga M, Godat S, Nydegger A, Moradpour D, Schoepfer AM. Calprotectine fecale: outil diagnostique dans les maladies inflammatoires chroniques de land;#39;intestin [Fecal calprotectin: a diagnostic tool for inflammatory bowel disease]. Rev Med Suisse. 2012 Sep 5;8(352):1669-70, 1672-3. French. PMID: 22988727.&#13;
	Panaccione R, Colombel JF, Louis E, Peyrin-Biroulet L, Sandborn WJ. Evolving definitions of remission in Crohnand;#39;s disease. Inflamm Bowel Dis. 2013 Jul;19(8):1645-53. doi: 10.1097/MIB.0b013e318283a4b3. PMID: 23598817.&#13;
	Stange EF, Travis SP, Vermeire S, Beglinger C, Kupcinkas L, Geboes K, Barakauskiene A, Villanacci V, Von Herbay A, Warren BF, Gasche C, Tilg H, Schreiber SW, Schand;ouml;lmerich J, Reinisch W; European Crohnand;#39;s and Colitis Organisation. European evidence based consensus on the diagnosis and management of Crohnand;#39;s disease: definitions and diagnosis. Gut. 2006 Mar;55 Suppl 1(Suppl 1):i1-15. doi: 10.1136/gut.2005.081950a. PMID: 16481628; PMCID: PMC1859998.&#13;
	Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohnand;#39;s disease activity index. National Cooperative Crohnand;#39;s Disease Study. Gastroenterology. 1976 Mar;70(3):439-44. PMID: 1248701.&#13;
	Gold SL, Rabinowitz LG, Manning L, Keefer L, Rivera-Carrero W, Stanley S, Sherman A, Castillo A, Tse S, Hyne A, Matos K, Cohen B, Grinspan A, Colombel JF, Sands BE, Dubinsky MC, Ungaro RC. High Prevalence of Malnutrition and Micronutrient Deficiencies in Patients With Inflammatory Bowel Disease Early in Disease Course. Inflamm Bowel Dis. 2023 Mar 1;29(3):423-429. doi: 10.1093/ibd/izac102. PMID: 35590456; PMCID: PMC9977243.&#13;
	Haskey N, Peand;ntilde;a-Sand;aacute;nchez JN, Jones JL, Fowler SA. Development of a screening tool to detect nutrition risk in patients with inflammatory bowel disease. Asia Pac J Clin Nutr. 2018;27(4):756-762. doi: 10.6133/apjcn.112017.01. PMID: 30045418&#13;
	Li S, Ney M, Eslamparast T, Vandermeer B, Ismond KP, Kroeker K, Halloran B, Raman M, Tandon P. Systematic review of nutrition screening and assessment in inflammatory bowel disease. World J Gastroenterol. 2019 Jul 28;25(28):3823-3837. doi: 10.3748/wjg.v25.i28.3823. PMID: 31391776; PMCID: PMC6676547.&#13;
	Bryant RV, Trott MJ, Bartholomeusz FD, Andrews JM. Systematic review: body composition in adults with inflammatory bowel disease. Aliment Pharmacol Ther. 2013 Aug;38(3):213-25. doi: 10.1111/apt.12372. Epub 2013 Jun 14. PMID: 23763279.&#13;
	Kyle UG, Piccoli A, Pichard C. Body composition measurements: interpretation finally made easy for clinical use. Curr Opin Clin Nutr Metab Care. 2003 Jul;6(4):387-93. doi: 10.1097/01.mco.0000078988.18774.3d. PMID: 12806211.&#13;
	Yadav DP, Kedia S, Madhusudhan KS, Bopanna S, Goyal S, Jain S, Vikram NK, Sharma R, Makharia GK, Ahuja V. Body Composition in Crohnand;#39;s Disease and Ulcerative Colitis: Correlation with Disease Severity and Duration. Can J Gastroenterol Hepatol. 2017;2017:1215035. doi: 10.1155/2017/1215035. Epub 2017 Oct 31. PMID: 29226115; PMCID: PMC5684551.&#13;
	Schutz Y, Kyle UU, Pichard C. Fat-free mass index and fat mass index percentiles in Caucasians aged 18-98 y. Int J Obes Relat Metab Disord. 2002 Jul;26(7):953-60. doi: 10.1038/sj.ijo.0802037. PMID: 12080449.&#13;
	Peng Z, Xu D, Li Y, Peng Y, Liu X. Phase Angle as a Comprehensive Tool for Nutritional Monitoring and Management in Patients with Crohnand;#39;s Disease. Nutrients. 2022 May 28;14(11):2260. doi: 10.3390/nu14112260. PMID: 35684060; PMCID: PMC9182801.&#13;
	Liu J, Ge X, Ouyang C, Wang D, Zhang X, Liang J, Zhu W, Cao Q. Prevalence of Malnutrition, Its Risk Factors, and the Use of Nutrition Support in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2022 Jun 2;28(Suppl 2):S59-S66. doi: 10.1093/ibd/izab345. PMID: 34984471; PMCID: PMC10686604.&#13;
	Ciocand;icirc;rlan M, Ciocand;icirc;rlan M, Iacob R, Tanand;#539;and;#259;u A, Gheorghe L, Gheorghe C, Dobru D, Constantinescu G, Cijevschi C, Trifan A, Goldiand;#537; A, Diculescu M. Malnutrition Prevalence in Newly Diagnosed Patients with Inflammatory Bowel Disease - Data from the National Romanian Database. J Gastrointestin Liver Dis. 2019 Jun 1;28:163-168. doi: 10.15403/jgld-176. PMID: 31204412.&#13;
	Papadimitriou K, Detopoulou P, Soufleris K, Voulgaridou G, Tsoumana D, Ntopromireskou P, Giaginis C, Chatziprodromidou IP, Spanoudaki M, Papadopoulou SK. Nutritional Risk and Sarcopenia Features in Patients with Crohnand;#39;s Disease: Relation to Body Composition, Physical Performance, Nutritional Questionnaires and Biomarkers. Nutrients. 2023 Aug 17;15(16):3615. doi: 10.3390/nu15163615. PMID: 37630805; PMCID: PMC10458234.&#13;
	Bian D, Shi Y, Jiang Y, Zhong J, Sun J, Gu Y. Combined Patient-Generated Subjective Global Assessment and body composition facilitates nutritional support in inflammatory bowel disease: an ambulatory study in Shanghai. Asia Pac J Clin Nutr. 2018;27(6):1230-1238. doi: 10.6133/apjcn.201811_27(6).0009. PMID: 30485921.&#13;
	Sandall AM, Wall CL, Lomer MCE. Nutrition Assessment in Crohnand;#39;s Disease using Anthropometric, Biochemical, and Dietary Indexes: A Narrative Review. J Acad Nutr Diet. 2020 Apr;120(4):624-640. doi: 10.1016/j.jand.2019.04.013. Epub 2019 Jun 24. PMID: 31248791.&#13;
	Lomer MC. Dietary and nutritional considerations for inflammatory bowel disease. Proc Nutr Soc. 2011 Aug;70(3):329-35. doi: 10.1017/S0029665111000097. Epub 2011 Mar 30. PMID: 21450124.&#13;
	Varma A, Weinstein J, Seabury J, Rosero S, Wagner E, Zizzi C, Luebbe E, Dilek N, McDermott M, Heatwole J, Saubermann L, Temple L, Rogoff S, Heatwole C. Patient-Reported Impact of Symptoms in Crohnand;#39;s Disease. Am J Gastroenterol. 2022 Dec 1;117(12):2033-2045. doi: 10.14309/ajg.0000000000001954. Epub 2022 Aug 22. PMID: 36375002; PMCID: PMC9722385.&#13;
	Lanfranchi GA, Brignola C, Campieri M, Bazzocchi G, Pasquali R, Bassein L, Laband;ograve; G. Assessment of nutritional status in Crohnand;#39;s disease in remission or low activity. Hepatogastroenterology. 1984 Jun;31(3):129-32. PMID: 6469202.&#13;
	Prieto JMI, Andrade AR, Magro DO, Imbrizi M, Nishitokukado I, Ortiz-Agostinho CL, Dos Santos FM, Luzia LA, Rondo PHC, Leite AZA, Carrilho FJ, Sipahi AM. Nutritional Global Status and Its Impact in Crohnand;#39;s Disease. J Can Assoc Gastroenterol. 2021 Mar 23;4(6):290-295. doi: 10.1093/jcag/gwab006. PMID: 34877468; PMCID: PMC8643688.&#13;
	Cury DB, Oliveira R, Cury MS. Inflammatory bowel diseases: time of diagnosis, environmental factors, clinical course, and management - a follow-up study in a private inflammatory bowel disease center (2003-2017). J Inflamm Res. 2019 May 28;12:127-135. doi: 10.2147/JIR.S190929. PMID: 31213873; PMCID: PMC6543909.&#13;
	Wei H, Yuan Z, Ren K, Jin Y, Ren L, Cao B, Zhou Y, Chen L. Body Composition in Inflammatory Bowel Disease. Arch Iran Med. 2023 Mar 1;26(3):172-175. doi: 10.34172/aim.2023.26. PMID: 37543940; PMCID: PMC10685726.&#13;
	Pulley J, Todd A, Flatley C, Begun J. Malnutrition and quality of life among adult inflammatory bowel disease patients. JGH Open. 2019 Nov 14;4(3):454-460. doi: 10.1002/jgh3.12278. PMID: 32514453; PMCID: PMC7273715.&#13;
	Benjamin J, Makharia GK, Kalaivani M, Joshi YK. Nutritional status of patients with Crohnand;#39;s disease. Indian J Gastroenterol. 2008 Sep-Oct;27(5):195-200. PMID: 19112190.&#13;
	Dranga M, Boiculese LV, Popa IV, Floria M, Gavril OI, Band;#259;rboi OB, Trifan A, Cijevschi Prelipcean C, Mihai C, Gavrilescu O. Anemia in Crohnand;#39;s Disease-The Unseen Face of Inflammatory Bowel Disease. Medicina (Kaunas). 2021 Sep 30;57(10):1046. doi: 10.3390/medicina57101046. PMID: 34684083; PMCID: PMC8539193.&#13;
	Nemeand;#351; RM, Pop CS, Calagiu D, Dobrin D, Chetroiu D, Jantea P, Postolache P. ANEMIA IN INFLAMMATORY BOWEL DISEASE MORE THAN AN EXTRAINTESTINAL COMPLICATION. Rev Med Chir Soc Med Nat Iasi. 2016 Jan-Mar;120(1):34-9. PMID: 27125070.&#13;
	Shepherd JA, Ng BK, Sommer MJ, Heymsfield SB. Body composition by DXA. Bone. 2017 Nov;104:101-105. doi: 10.1016/j.bone.2017.06.010. Epub 2017 Jun 16. PMID: 28625918; PMCID: PMC5659281.</References>
      </References>
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