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<Journal>
<PublisherName>journal-jmsr</PublisherName>
<JournalTitle>Journal of Medical and Surgical Research</JournalTitle>
<PISSN>I</PISSN>
<EISSN>S</EISSN>
<Volume-Issue>Vol. IX, n 2</Volume-Issue>
<PartNumber/>
<IssueTopic>Multidisciplinary</IssueTopic>
<IssueLanguage>English</IssueLanguage>
<Season>December 2022</Season>
<SpecialIssue>N</SpecialIssue>
<SupplementaryIssue>N</SupplementaryIssue>
<IssueOA>Y</IssueOA>
<PubDate>
<Year>-0001</Year>
<Month>11</Month>
<Day>30</Day>
</PubDate>
<ArticleType>JMSR Surgery</ArticleType>
<ArticleTitle>Factors Impacting Mortality In Turkish Octogenarian and Nonagenarian Patients Who Underwent Colorectal Surgery</ArticleTitle>
<SubTitle/>
<ArticleLanguage>English</ArticleLanguage>
<ArticleOA>Y</ArticleOA>
<FirstPage>1136</FirstPage>
<LastPage>1141</LastPage>
<AuthorList>
<Author>
<FirstName>Cengiz</FirstName>
<LastName>Ceylan</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>N</CorrespondingAuthor>
<ORCID/>
<FirstName>Serhat</FirstName>
<LastName>Ocakli</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Felat</FirstName>
<LastName>Akinci</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Erdinc</FirstName>
<LastName>Cetinkaya</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Ibrahim</FirstName>
<LastName>Agackiran</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Tezcan</FirstName>
<LastName>Akin</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
<FirstName>Sadettin</FirstName>
<LastName>Er</LastName>
<AuthorLanguage>English</AuthorLanguage>
<Affiliation/>
<CorrespondingAuthor>Y</CorrespondingAuthor>
<ORCID/>
</Author>
</AuthorList>
<DOI>10.46327/msrjg.1.000000000000228</DOI>
<Abstract>Background __ampersandsign objective: Due to their physiological conditions, the postoperative mortality rates of elderly patients are higher compared to other age groups, albeit the postoperative care and intensive care conditions are better than in the past. In this retrospective study, it was aimed to present a model to predict mortality and factors affecting mortality in this patient group who underwent colorectal surgery. Material __ampersandsign Methods: The population of octogenarian and nonagenarian patients who were operated for colorectal surgery in our clinic between 2020 and 2021 were included in the study. Patients__ampersandsign#39; age, gender, albumin, lymphocyte, monocytes, lymphocyte-monocyte ratio (LMR), prognostic nutritional index (PNI), delta neutrophil index (DNI), Charlson comorbidity index (CCI), length of hospital stay, modified systemic inflammatory score (mSIS)) values, operation type (emergency/ elective), operation classification (minor/ moderate/ major/ complex major), anesthesia type (general/ epidural), and contamination status (clean/ clean-contaminated/ contaminated/ dirty or infected) were obtained from the hospital system. Results: Case status, operation type, contamination status, DNI, duration of hospitalization, mSIS variables were statistically significant in univariate regression analyses. However, in multivariate regression analyses, DNI of ? 0.05 (p< 0.015; OR 3.984, 95%CI 1.302- 12.195) and contamination status (p< 0.038; OR 13,047, 95%Cl 1,150- 148,087) were found to be independent risk factors affecting postoperative mortality. Conclusion: In the geriatric patient population undergoing colorectal surgery, DNI and contamination of the surgical field are two important factors affecting mortality. We think that the mortality estimation model created for this patient population will also help physicians for the postoperative period of the patients.</Abstract>
<AbstractLanguage>English</AbstractLanguage>
<Keywords>Colorectal Surgery, Mortality, Model, Nonagenarian, Octogenerian,Turkey</Keywords>
<URLs>
<Abstract>https://www.journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=14278&title=Factors Impacting Mortality In Turkish Octogenarian and Nonagenarian Patients Who Underwent Colorectal Surgery</Abstract>
</URLs>
<References>
<ReferencesarticleTitle>References</ReferencesarticleTitle>
<ReferencesfirstPage>16</ReferencesfirstPage>
<ReferenceslastPage>19</ReferenceslastPage>
<References>Aceto P, Antonelli Incalzi R, Bettelli G, Carron M, Chiumiento F, Corcione A, Crucitti A, Maggi S, Montorsi M, Pace MC, Petrini F, Tommasino C, Trabucchi M, Volpato S; Societand;agrave; Italiana di Anestesia Analgesia Rianimazione e Terapia Intensiva (SIAARTI), Societand;agrave; Italiana di Gerontologia e Geriatria (SIGG), Societand;agrave; Italiana di Chirurgia (SIC), Societand;agrave; Italiana di Chirurgia Geriatrica (SICG) and Associazione Italiana di Psicogeriatria (AIP). Perioperative Management of Elderly patients (PriME): recommendations from an Italian intersociety consensus. Aging Clin Exp Res. 2020;32(9):1647-1673.
Asmis TR, Din K, Seymour L, Shepher FA, Leighl NB, Winton TL, Whitehead M, Spaans JN, Graham BC, Goss GD, and; National Cancer Institute of Canada Clinical Trials Group. Age and comorbidity as independent prognostic factors in the treatment of non small-cell lung cancer: a review of National Cancer Institute of Canada Clinical Trials Group trials. J Clin Oncol. 2008;26(1):54-59.
Robinson TN, Eiseman B, Wallace JI, Church SD, McFann KK, Pfister SM, Sharp TJ, Moss M. Redefining geriatric preoperative assessment using frailty, disability and co-morbidity. Ann Surg. 2009;250(3):449-55.
Pasetto LM, Lise M, Monfardini S. Preoperative assessment of elderly cancer patients. Crit Rev Oncol Hematol. 2007;64(1):10-8. doi: 10.1016/j.critrevonc.2007.08.001. PMID: 17826628.
Loran DB, Zwischenberger JB. Thoracic surgery in the elderly. J Am Coll Surg. 2004;199(5):773-84.
Rosenthal RA. Nutritional concerns in the older surgical patient. J Am Coll Surg. 2004;199:785-791.
Tekkis PP, Kinsman R, Thompson MR, Stamatakis JD; Association of Coloproctology of Great Britain, Ireland. The Association of Coloproctology of Great Britain and Ireland study of large bowel obstruction caused by colorectal cancer. Ann Surg. 2004;240(1):76-81.
Chang TT, Schecter WP. Injury in the elderly and end-of-life decisions. Surg Clin North Am. 2007;87(1):229-45, viii.
Green G, Shaikh I, Fernandes R, Wegstapel H. Emergency laparotomy in octogenarians: a 5-year study of morbidity and mortality. World J Gastrointest Surg 2013;5(7):216-221
Rubinfeld I, Thomas C, Berry S, Murthy R, Obeid N, Azuh O, Jordan J, Patton JH. Octogenarian abdominal surgical emergencies: not so grim a problem with the acute care surgery model? J Trauma. 2009;67(5):983-9.
Hentati H, Salloum C, Caillet P, Lahat E, Disabato M, Levesque E, Compagnon P, Lim C, Azoulay D. Risk Factors for Mortality and Morbidity in Elderly Patients Presenting with Digestive Surgical Emergencies. World J Surg. 2018;42(7):1988-1996.
Massarweh NN, Legner VJ, Symons RG, McCormick WC, Flum DR. Impact of advancing age on abdominal surgical outcomes. Arch Surg. 2009;144(12):1108-14.
Tan KY, Chen CM, Ng C, Tan SM, Tay KH. Which octogenarians do poorly after major open abdominal surgery in our Asian population? World J Surg. 2006;30(4):547-52.
Griner D, Adams A, Kotwall CA, Clancy TV, Hope WW. After-hours urgent and emergent surgery in the elderly: outcomes and prognostic factors. Am Surg. 2011;77(8):1021-4.
Zerbib P, Kulick JF, Lebuffe G, Khoury-Helou A, Plenier I, Chambon JP. Emergency major abdominal surgery in patients over 85 years of age. World J Surg. 2005;29(7):820-5.
Clarke A, Murdoch H, Thomas MJ, Cook TM, Peden CJ. Mortality and postoperative care after emergency laparotomy. Eur J Anaesthesiol. 2011;28(1):16-9.
Roque-Castellano C, Marchena-Gand;oacute;mez J, Fariand;ntilde;a-Castro R, Acosta-Mand;eacute;rida MA, Armas-Ojeda MD, Sand;aacute;nchez-Guand;eacute;dez MI. Perioperative Blood Transfusion is Associated with an Increased Mortality in Older Surgical Patients. World J Surg. 2016;40(8):1795-801.
Kim HW, Ku S, Jeong SJ, Jin SJ, Han SH, Choi JY, Kim JM, Song YG. Delta neutrophil index: could it predict mortality in patients with bacteraemia? Scand J Infect Dis. 2012;44(7):475-80.
Park BH, Kang YA, Park MS, Jung WJ, Lee SH, Lee SK, Kim SY, Kim SK, Chang J, Jung JY, Kim YS. Delta neutrophil index as an early marker of disease severity in critically ill patients with sepsis. BMC Infect Dis. 2011;11:299.
Bang HJ, Kim K, Shim H, Kim S, Jung PY, Choi YU, Bae KS, Kim IY, Jang JY. Delta neutrophil index for predicting mortality in trauma patients who underwent emergent abdominal surgery: A case controlled study. PLoS One. 2020;15(3):e0230149.
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001;357(9255):539-45.
Suzuki Y, Okabayashi K, Hasegawa H, Tsuruta M, Shigeta K, Kondo T, Kitagawa Y. Comparison of Preoperative Inflammation-based Prognostic Scores in Patients With Colorectal Cancer. Ann Surg. 2018;267(3):527-531.
Chang Y, An H, Xu L, Zhu Y, Yang Y, Lin Z, Xu J. Systemic inflammation score predicts postoperative prognosis of patients with clear-cell renal cell carcinoma. Br J Cancer. 2015;113(4):626-33.
Lin JX, Lin JP, Xie JW, Wang JB, Lu J, Chen QY, Cao LL, Lin M, Tu R, Zheng CH, Huang CM, Li P. Prognostic importance of the preoperative modified systemic inflammation score for patients with gastric cancer. Gastric Cancer. 2019;22(2):403-412.
Inagaki K, Kanda M, Nakanishi K, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y. Accurate Prediction of Prognosis After Radical Resection of Gastric Cancer by the Modified Systemic Inflammation Score; a Multicenter Dataset Analysis. World J Surg. 2021; 45 (8): 2513-20</References>
</References>
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