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Plasma Rich in Growth Factors in Forefoot Reconstruction Surgery

Author: Abo Zaalan Wessam, Levon Gagikovich Makinyan, Nikolai Vasilivich Zagorodniy, Arsen Yusufovich Khubiev, Abdul Basith Shahul Hameed

Category: JMSR Surgery


Plasma rich in growth factors (PRGF) is a successful therapy in various sectors of medicines in the present decade. Its effectiveness in forefoot surgery is still unknown. The aim of our study is to analyze the outcomes of forefoot surgeries with the infiltration of PRGF. One hundred and eighty patients were divided into 2 groups. The first group included 90 patients where only forefoot reconstruction was performed, whereas, in the second group PRGF was added. Scarf and Wilson osteotomies were performed for hallux valgus and tailor’s bunion respectively. Clinical and radiological outcomes were monitored in both groups pre and postoperatively. The mean postoperative AOFAS scores were 67.82 (range: 32 – 82) and the mean postoperative Foot Function Index (FFI) was 0.51 (range: 0.23 to 0.63) in the PRGF group. Ninety percent (162/180 feet) reported early pain relief, improved cosmetic appearance and improved footwear comfort. The mean hallux valgus angles improved from 30° to 15°, 1st IMA from 15° to 8° and 4-5 IMA from a mean of 11° to 7° in both groups. Four feet had non-union of the Scarf osteotomy and three of them were re-operated. PRGF stimulates cell viability and proliferation and enhances the surgical treatment of forefoot deformities by reducing postoperative pain, edema, and rehabilitation period and improves cosmesis and comfort.

Keywords: PRGF, Hallux valgus, Tailor Bunion, Scarf osteotomy, Wilson osteotomy, AOFAS, Foot Function Index

DOI: 10.46327/msrjg.1.000000000000222



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