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  <Article>
    <Journal>
      <PublisherName>journal-jmsr</PublisherName>
      <JournalTitle>Journal of Medical and Surgical Research</JournalTitle>
      <PISSN>I</PISSN>
      <EISSN>S</EISSN>
      <Volume-Issue>Vol. VI, n 2</Volume-Issue>
      <PartNumber/>
      <IssueTopic>Multidisciplinary</IssueTopic>
      <IssueLanguage>English</IssueLanguage>
      <Season>December 2019</Season>
      <SpecialIssue>N</SpecialIssue>
      <SupplementaryIssue>N</SupplementaryIssue>
      <IssueOA>Y</IssueOA>
      <PubDate>
        <Year>-0001</Year>
        <Month>11</Month>
        <Day>30</Day>
      </PubDate>
      <ArticleType>JMSR Obstetrics &amp; Gynecology</ArticleType>
      <ArticleTitle>New-Onset Granulomatous Mastitis in a Systemic Lupus Erythematosus Patient While on Immunosuppressive</ArticleTitle>
      <SubTitle/>
      <ArticleLanguage>English</ArticleLanguage>
      <ArticleOA>Y</ArticleOA>
      <FirstPage>639</FirstPage>
      <LastPage>641</LastPage>
      <AuthorList>
        <Author>
          <FirstName>Mehmet Engin</FirstName>
          <LastName>Tezcan</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>N</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Kenan</FirstName>
          <LastName>Cetin</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Seda</FirstName>
          <LastName>Mazmanoglu</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
          <FirstName>Nimet</FirstName>
          <LastName>Karaday?</LastName>
          <AuthorLanguage>English</AuthorLanguage>
          <Affiliation/>
          <CorrespondingAuthor>Y</CorrespondingAuthor>
          <ORCID/>
        </Author>
      </AuthorList>
      <DOI/>
      <Abstract>Etiology of granulomatous mastitis (GM) mostly unknown, but it may be associated with systemic or local granulomatous diseases. It responds well to immunosuppressive treatments. Here, we reported a case of a 36 year- old female systemic lupus erythematosus (SLE) patient with a new onset breast mass at the first year of the disease. Meanwhile, she was taking azathiopurine, hydroxychloriquine and low dosage steroid treatment during the onset of the breast mass. Then, granulomatous inflammation was found at the biopsy from the breast lesion. After, excluding the possible infectious etiologies, we started high dosage steroid. Thereafter, GM was responded to the treatment and then, she has been free of relapse since reducing the dosage of steroid to moderate level. As far as we know, our patient was the first SLE associated GM case resistant to treatment of azathiopurine and hydroxychloriquine. Moreover, we thought that GM may occur during immunosuppressive treatments in SLE patients and responded to high dosage of steroid.</Abstract>
      <AbstractLanguage>English</AbstractLanguage>
      <Keywords>Azathiopurine, Granulomatous mastitis, Hydroxychloriquine, Systemic erythematosus lupus</Keywords>
      <URLs>
        <Abstract>https://www.journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=6694&amp;title=New-Onset Granulomatous Mastitis in a Systemic Lupus Erythematosus Patient While on Immunosuppressive</Abstract>
      </URLs>
      <References>
        <ReferencesarticleTitle>References</ReferencesarticleTitle>
        <ReferencesfirstPage>16</ReferencesfirstPage>
        <ReferenceslastPage>19</ReferenceslastPage>
        <References>1 Ocal K, Dag A, Turkmenoglu O, Kara T, Seyit H,Konca K. Granulomatous mastitis: clinical, pathological features, and management. Breast J. 2010;16(2):176-82.&#13;
&#13;
2 Rose CD, Neven B,Wouters C. Granulomatous inflammation: The overlap of immune deficiency and inflammation. Best Pract Res Clin Rheumatol. 2014;28(2):191-212.&#13;
&#13;
3 Gautier N, Lalonde L, Tran-Thanh D, El Khoury M, David J, Labelle M, et al. Chronic granulomatous mastitis: Imaging, pathology and management. Eur J Radiol. 2013;82(4):e165-75.&#13;
&#13;
4 Barreto DS, Sedgwick EL, Nagi CS,Benveniste AP. Granulomatous mastitis: etiology, imaging, pathology, treatment, and clinical findings. Breast Cancer Res Treat. 2018;171(3):527-534.&#13;
&#13;
5 Chu AN, Seiler SJ, Hayes JC, Wooldridge R,Porembka JH. Magnetic resonance imaging characteristics of granulomatous mastitis. Clin Imaging. 2017;43(199-201.&#13;
&#13;
6 Raj N, Macmillan RD, Ellis IO,Deighton CM. Rheumatologists and breasts: immunosuppressive therapy for granulomatous mastitis. Rheumatology (Oxford). 2004;43(8):1055-6.&#13;
&#13;
7 Zhang LN, Shi TY, Yang YJ,Zhang FC. An SLE patient with prolactinoma and recurrent granulomatous mastitis successfully treated with hydroxychloroquine and bromocriptine. Lupus. 2014;23(4):417-20.&#13;
&#13;
8 Sellitto A, Santoriello A, De Fanis U, Benevento R, Perna G, Rossiello R, et al. Granulomatous lobular mastitis: another manifestation of systemic lupus erythematosus? Breast J. 2013;19(3):331-2.&#13;
&#13;
9 Konan A, Kalyoncu U, Dogan I, Kilic YA, Karakoc D, Akdogan A, et al. Combined long-term steroid and immunosuppressive treatment regimen in granulomatous mastitis. Breast Care (Basel). 2012;7(4):297-301.</References>
      </References>
    </Journal>
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