<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>journal-jmsr</PublisherName> <JournalTitle>Journal of Medical and Surgical Research</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Vol. III, n 2</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>December 2016</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>-0001</Year> <Month>11</Month> <Day>30</Day> </PubDate> <ArticleType>JMSR Nephrology</ArticleType> <ArticleTitle>Renal Biopsy in Lupus Nephropathy: General Features and Preditors of Bad Prognosis.</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>286</FirstPage> <LastPage>295</LastPage> <AuthorList> <Author> <FirstName>Mikou</FirstName> <LastName>Souad</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Tarik</FirstName> <LastName>Sqalli</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Mohammed</FirstName> <LastName>Arryhani</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>Introduction: Lupus nephritis is one of the most serious manifestations of systemic lupus erythematosus (SLE). It__ampersandsign#39;s responsible for a high morbid-mortality in young subjects. The aim of our study is to establish lupus nephritis epidemiology in our population, histological features and predictive factors of proliferative and active injuries and predictors of bad prognosis. Results: Were enrolled 71 biopsies finding lupus nephritis among 700 kidney biopsies conducted in our nephrology department during the period of 6 years (10.14%).The average age of patients was 32.69 ---PlusMinusSymbol--- 11.48 years. A female predominance was observed (sex-ratio =0.2). The main indication for biopsy was the concomitant existence of proteinuria, hematuria and renal failure (48%). In univariate analysis, we retained as predictive factors of proliferative and active form: spring season flare with a maximum in June, pre-existing lupus nephritis, lymphopenia and nephrotic syndrome. Risks of progression to chronic renal failure were: female gender in 90% of cases (p</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Classification, Lupus Nephritis, Renal Biopsy, Prognosis, Spring</Keywords> <URLs> <Abstract>https://www.journal-jmsr.net/ubijournal-v1copy/journals/abstract.php?article_id=4793&title=Renal Biopsy in Lupus Nephropathy: General Features and Preditors of Bad Prognosis.</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References>Schwartz MM, Kawala KS, Corwin HL, Lewis EJ. The prognosis of segmental glomerulonephritis in systemic lupus erythematosus. Kidney Int 1987; 32:274. Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P, et al. Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1000 patients. 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